CARM1 antibody (AA 409-608)

Catalog No. ABIN1682307

The Rabbit Polyclonal anti-CARM1 antibody (ABIN1682307) specifically detects CARM1 in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for CARM1 antibody (AA 409-608) (ABIN1682307)

Target: CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CARM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CARM1 Antibody

Binding Specificity: AA 409-608

Sequence: TEPLTHWYQV RCLFQSPLFA KAGDTLSGTC LLIANKRQSY DISIVAQVDQ TGSKSSNLLD LKNPFFRYTG TTPSPPPGSH YTSPSENMWN TGSTYNLSSG MAVAGMPTAY DLSSVIASGS SVGHNNLIPL ANTGIVNHTH SRMGSIMSTG IVQGSSGAQG SGGGSTSAHY AVNSQFTMGG PAISMASPMS IPTNTMHYGS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 409-608 of human PRMT4/CARM1 (NP_954592.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CARM1

Target: CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))

Alternative Name: CARM1

Background: This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts specifically on histones and other chromatin-associated proteins and is involved in regulation of gene expression. The enzyme may act in association with other proteins or within multi-protein complexes and may play a role in cell type-specific functions and cell lineage specification. A related pseudogene is located on chromosome 9.,CARM1,PRMT4,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Methylation,Nuclear Receptor Signaling,Nuclear hormone receptors,Cancer,Tumor suppressors,p53 pathway,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Endocrine & Metabolism,Lipid Metabolism,CARM1

Molecular Weight: 41 kDa/63 kDa/65 kDa

Gene ID: 10498

UniProt: Q86X55

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of fat Cell Differentiation