PUM1 antibody

Catalog No. ABIN1682469

This anti-PUM1 antibody is a Rabbit Monoclonal antibody detecting PUM1 in WB and IF. Suitable for Human.

Quick Overview for PUM1 antibody (ABIN1682469)

Target: PUM1 (Pumilio Homolog 1 (PUM1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PUM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-PUM1 Antibody

Cross-Reactivity: Human, Mouse

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Pumilio 1

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PUM1

Target: PUM1 (Pumilio Homolog 1 (PUM1))

Alternative Name: PUM1

Background: This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],HSPUM, PUMH, PUMH1, PUML1,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,Germline Stem Cells,RNA Binding,Stem Cells,PUM1

Molecular Weight: 140 kDa

Gene ID: 9698

UniProt: Q14671