STAM antibody (AA 120-210)

Catalog No. ABIN1682903

The Rabbit Polyclonal anti-STAM antibody has been validated for WB and IHC. It is suitable to detect STAM in samples from Human.

Quick Overview for STAM antibody (AA 120-210) (ABIN1682903)

Target: STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAM antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-STAM Antibody

Binding Specificity: AA 120-210

Sequence: KNDPQLSLIS AMIKNLKEQG VTFPAIGSQA AEQAKASPAL VAKDPGTVAN KKEEEDLAKA IELSLKEQRQ QSTTLSTLYP STSSLLTNHQ H

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-210 of human STAM (NP_003464.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:1000,IHC,1:20 - 1:100

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for STAM

Target: STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))

Alternative Name: STAM

Background: This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene.,STAM,STAM-1,STAM1,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,STAM

Molecular Weight: 44 kDa/59 kDa

Gene ID: 8027

UniProt: Q92783

Pathways: EGFR Signaling Pathway, EGFR Downregulation