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Thrombomodulin antibody (AA 200-500)

The Rabbit Polyclonal anti-Thrombomodulin antibody has been validated for WB, IHC and IF. It is suitable to detect Thrombomodulin in samples from Human.
Catalog No. ABIN1683026

Quick Overview for Thrombomodulin antibody (AA 200-500) (ABIN1683026)

Target

See all Thrombomodulin (THBD) Antibodies
Thrombomodulin (THBD)

Reactivity

  • 130
  • 39
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  • 1
Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This Thrombomodulin antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • Binding Specificity

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    AA 200-500

    Sequence

    RGADFQALPV GSSAAVAPLG LQLMCTAPPG AVQGHWAREA PGAWDCSVEN GGCEHACNAI PGAPRCQCPA GAALQADGRS CTASATQSCN DLCEHFCVPN PDQPGSYSCM CETGYRLAAD QHRCEDVDDC ILEPSPCPQR CVNTQGGFEC HCYPNYDLVD GECVEPVDPC FRANCEYQCQ PLNQTSYLCV CAEGFAPIPH EPHRCQMFCN QTACPADCDP NTQASCECPE GYILDDGFIC TDIDECENGG FCSGVCHNLP GTFECICGPD SALARHIGTD CDSGKVDGGD SGSGEPPPSP T

    Cross-Reactivity

    Human, Mouse, Rat

    Characteristics

    Polyclonal Antibodies

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 200-500 of human THBD (NP_000352.1).

    Isotype

    IgG
  • Application Notes

    WB,1:200 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    Restrictions

    For Research Use only
  • Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    Thrombomodulin (THBD)

    Alternative Name

    THBD

    Background

    The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.,THBD,AHUS6,BDCA3,CD141,THPH12,THRM,TM,Immunology & Inflammation,CD markers,Stem Cells,Endothelial Progenitors,Cardiovascular,Cardiovascular Markers,Endothelial Cells,Blood,Coagulation,THBD

    Molecular Weight

    60 kDa

    Gene ID

    7056

    UniProt

    P07204
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