AKR7A2 antibody (AA 100-359)

Catalog No. ABIN3021782

The Rabbit Polyclonal anti-AKR7A2 antibody has been validated for WB. It is suitable to detect AKR7A2 in samples from Human.

Quick Overview for AKR7A2 antibody (AA 100-359) (ABIN3021782)

Target: AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKR7A2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AKR7A2 Antibody

Binding Specificity: AA 100-359

Sequence: VKIATKANPW DGKSLKPDSV RSQLETSLKR LQCPQVDLFY LHAPDHGTPV EETLHACQRL HQEGKFVELG LSNYASWEVA EICTLCKSNG WILPTVYQGM YNATTRQVET ELFPCLRHFG LRFYAYNPLA GGLLTGKYKY EDKDGKQPVG RFFGNSWAET YRNRFWKEHH FEAIALVEKA LQAAYGASAP SVTSAALRWM YHHSQLQGAH GDAVILGMSS LEQLEQNLAA TEEGPLEPAV VDAFNQAWHL VAHECPNYFR

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 100-359 of human AKR7A2 (NP_003680.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for AKR7A2

Target: AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))

Alternative Name: AKR7A2

Background: The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants.,AKR7A2,AFAR,AFAR1,AFB1-AR1,AKR7,Signal Transduction,Endocrine & Metabolism,Neuroscience,Neurodegenerative Diseases,AKR7A2

Molecular Weight: 39 kDa

Gene ID: 8574

UniProt: O43488