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AKR7A2 antibody (Internal Region)

AKR7A2 Reactivity: Human, Mouse, Rat ELISA, IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6259864
$390.77
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  • Target See all AKR7A2 Antibodies
    AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))
    Binding Specificity
    • 2
    • 2
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 23
    • 13
    • 11
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 16
    • 7
    Rabbit
    Clonality
    • 16
    • 7
    Polyclonal
    Conjugate
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This AKR7A2 antibody is un-conjugated
    Application
    • 9
    • 5
    • 3
    • 3
    • 1
    ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
    Specificity
    AKR7A2 Antibody detects endogenous levels of total AKR7A2.
    Predicted Reactivity
    Pig,Bovine,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human AKR7A2, corresponding to a region within the internal amino acids.
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))
    Alternative Name
    AKR7A2 (AKR7A2 Products)
    Synonyms
    AFAR antibody, AFAR1 antibody, AFB1-AR1 antibody, AKR7 antibody, Aiar antibody, akr7a2 antibody, aldo-keto reductase family 7 member A2 antibody, aldo-keto reductase family 7, member A2 antibody, aldo-keto reductase family 7, member A2 L homeolog antibody, AKR7A2 antibody, Akr7a2 antibody, akr7a2.L antibody
    Background

    Description: Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.

    Gene: AKR7A2

    Molecular Weight
    40kDa
    Gene ID
    8574
    UniProt
    O43488
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