TLR1 antibody (AA 30-290)

Catalog No. ABIN3023655

Product Details anti-TLR1 Antibody

Target: TLR1 (Toll-Like Receptor 1 (TLR1))

Binding Specificity: AA 30-290

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: DRSKNGLIHV PKDLSQKTTI LNISQNYISE LWTSDILSLS KLRILIISHN RIQYLDISVF KFNQELEYLD LSHNKLVKIS CHPTVNLKHL DLSFNAFDAL PICKEFGNMS QLKFLGLSTT HLEKSSVLPI AHLNISKVLL VLGETYGEKE DPEGLQDFNT ESLHIVFPTN KEFHFILDVS VKTVANLELS NIKCVLEDNK CSYFLSILAK LQTNPKLSNL TLNNIETTWN SFIRILQLVW HTTVWYFSIS NVKLQGQLDF R

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-290 of human TLR1 (NP_003254.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TLR1

Target: TLR1 (Toll-Like Receptor 1 (TLR1))

Alternative Name: TLR1 (TLR1 Products)

Background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.,TLR1,CD281,TIL,TIL. LPRS5,rsc786,TIL.LPRS5,Signal Transduction,Immunology & Inflammation,CD markers,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,TLR1

Molecular Weight: 90 kDa

Gene ID: 7096

UniProt: Q15399

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades