DICER1 antibody (AA 1638-1899)
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- Target See all DICER1 Antibodies
- DICER1 (Dicer 1, Ribonuclease Type III (DICER1))
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Binding Specificity
- AA 1638-1899
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Reactivity
- Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This DICER1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificity
- Detects ~215 kDa.
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Protein G Purified
- Immunogen
- Fusion protein amino acids 1638-1899 of mouse Endoribonuclease Dicer
- Clone
- S167-7
- Isotype
- IgG1
- Top Product
- Discover our top product DICER1 Primary Antibody
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anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 6-290) antibody
DICER1 Reactivity: Human WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated
anti-Dicer 1, Ribonuclease Type III (DICER1) antibodyDICER1 Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1-195) antibodyDICER1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1638-1899) antibody (HRP)DICER1 Reactivity: Mouse WB, ICC, IF Host: Mouse Monoclonal S167-7 HRP
anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1638-1899) antibody (Biotin)DICER1 Reactivity: Mouse WB, ICC, IF Host: Mouse Monoclonal S167-7 Biotin
anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1638-1899) antibody (FITC)DICER1 Reactivity: Mouse WB, ICC, IF Host: Mouse Monoclonal S167-7 FITC
anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1638-1899) antibody (APC)DICER1 Reactivity: Mouse WB, ICC, IF Host: Mouse Monoclonal S167-7 APC
anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1638-1899) antibody (PE)DICER1 Reactivity: Mouse WB, ICC, IF Host: Mouse Monoclonal S167-7 PE
anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1638-1899) antibody (PerCP)DICER1 Reactivity: Mouse WB, ICC, IF Host: Mouse Monoclonal S167-7 PerCP
anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1638-1899) antibody (Atto 488)DICER1 Reactivity: Mouse WB, ICC, IF Host: Mouse Monoclonal S167-7 Atto 488
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- Application Notes
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- Comment
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1 μg/ml of ABIN1686625 was sufficient for detection of Dicer in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- DICER1 (Dicer 1, Ribonuclease Type III (DICER1))
- Alternative Name
- Dicer (DICER1 Products)
- Background
- Dicer is a member of the RNase III family that specifically cleaves double-stranded RNAs to generate microRNAs (miRNAs) (1). After long primary transcript pri-miRNAs are processed to stem-looped pre-miRNAs by Drosha (2), pre-miRNAs are transported to the cytoplasm and further processed by Dicer to produce 22-nucleotide mature miRNAs (3). The mature miRNA then becomes a part of the RNA-Induced Silencing Complex (RISC) and can bind to the 3' UTR of the target mRNA (3)
- Gene ID
- 192119
- NCBI Accession
- NP_683750
- UniProt
- Q8R418
- Pathways
- Regulatory RNA Pathways, Stem Cell Maintenance, Ribonucleoprotein Complex Subunit Organization
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