DICER1 antibody (AA 6-290)

Catalog No. ABIN7436789

The Rabbit Polyclonal anti-DICER1 antibody is suitable to detect DICER1 in samples from Human. It has been validated for WB, IHC, ICC and IP.

Quick Overview for DICER1 antibody (AA 6-290) (ABIN7436789)

Target: DICER1 (Dicer 1, Ribonuclease Type III (DICER1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DICER1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Product Details anti-DICER1 Antibody

Binding Specificity: AA 6-290

Purpose: Polyclonal Antibody to Dicer 1, Ribonuclease Type III (DICER1)

Specificity: The antibody is a rabbit polyclonal antibody raised against DICER1. It has been selected for its ability to recognize DICER1 in immunohistochemical staining and western blotting.

Cross-Reactivity: Mouse, Rat

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Dicer 1, Ribonuclease Type III (DICER1) corresdonding to Leu6~Ser290 with N-terminal His Tag

Isotype: IgG

Application Details

Application Notes: Western blotting: 0.01-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Immunocytochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Preservative: ProClin, Sodium azide

Precaution of Use: This product contains ProClin and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for DICER1

Target: DICER1 (Dicer 1, Ribonuclease Type III (DICER1))

Alternative Name: DICER1

Background: Dicer, HERNA, Dicer 1,Double-Stranded RNA-Specific Endoribonuclease, Helicase with RNase motif, Helicase MOI

UniProt: Q9UPY3

Pathways: Regulatory RNA Pathways, Stem Cell Maintenance, Ribonucleoprotein Complex Subunit Organization