GMP Synthase antibody (AA 301-400) (AbBy Fluor® 350)

Catalog No. ABIN1693050

This anti-GMP Synthase antibody is a Rabbit Polyclonal antibody detecting GMP Synthase in WB, IF (cc) and IF (p). Suitable for Human.

Quick Overview for GMP Synthase antibody (AA 301-400) (AbBy Fluor® 350) (ABIN1693050)

Target: GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GMP Synthase antibody is conjugated to AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-GMP Synthase Antibody (AbBy Fluor® 350)

Binding Specificity: AA 301-400

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GMP Synthase

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GMP Synthase

Target: GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))

Alternative Name: GMP Synthase

Background:

Synonyms: GMPS, Glutamine amidotransferase, GMP synthase [glutamine hydrolyzing], GMP synthase [glutamine-hydrolyzing], GMP synthetase, Gmps, GUAA_HUMAN, Guanine monphosphate synthetase, MLL/GMPS fusion protein.

Background: In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP. [provided by RefSeq, Jul 2008].

Gene ID: 8833

Pathways: Ribonucleoside Biosynthetic Process