CWC22 antibody (AA 101-200) (AbBy Fluor® 350)

Catalog No. ABIN1693369

This Rabbit Polyclonal antibody specifically detects CWC22 in IF (cc) and IF (p). It exhibits reactivity toward Mouse and Rat.

Quick Overview for CWC22 antibody (AA 101-200) (AbBy Fluor® 350) (ABIN1693369)

Target: CWC22 (CWC22 Spliceosome-Associated Protein Homolog (CWC22))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CWC22 antibody is conjugated to AbBy Fluor® 350

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CWC22 Antibody (AbBy Fluor® 350)

Binding Specificity: AA 101-200

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CWC22

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CWC22

Target: CWC22 (CWC22 Spliceosome-Associated Protein Homolog (CWC22))

Alternative Name: CWC22

Background:

Synonyms: CWC22, CWC22 spliceosome associated protein homolog S. cerevisiae, CWC22 spliceosome associated protein homolog, CWC22_HUMAN, E4GL, fSAPb, Functional spliceosome associated protein b, KIAA1604, NCM, Nucampholin homolog, Pre-mRNA-splicing factor CWC22 homolog.

Background: Spliceosomes are multi-protein complexes that are composed of snRNPs (small nuclear ribonucleoproteins) and a variety of associated protein factors, all of which work in concert to regulate the splicing of pre-mRNA, a critical step in the post-transcriptional regulation of gene expression. CWC22 (CWC22 spliceosome-associated protein), also known as NCM, fSAPb or EIF4GL, is a 908 amino acid nuclear protein and component of the spliceosome C complex. CWC22 is associated with the spliceosome prior to catalytic steps and remains associated throughout the reaction. Belonging to the CWC22 family, CW22 contains one MI domain and a MIF4G domain. The gene encoding CWC22 maps to human chromosome 2q31.3. As the second largest human chromosome, chromosome 2 makes up approximately 8 % of the human genome and contains 237 million bases encoding over 1,400 genes.

Gene ID: 57703