ATF5 antibody (AbBy Fluor® 350)

Catalog No. ABIN1693894

This Rabbit Polyclonal antibody specifically detects ATF5 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ATF5 antibody (AbBy Fluor® 350) (ABIN1693894)

Target: ATF5 (Activating Transcription Factor 5 (ATF5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATF5 antibody is conjugated to AbBy Fluor® 350

Application: Western Blotting (WB)

Product Details anti-ATF5 Antibody (AbBy Fluor® 350)

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ATF5

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ATF5

Target: ATF5 (Activating Transcription Factor 5 (ATF5))

Alternative Name: Atf5

Background:

Synonyms: Activating transcription factor 5 alpha/beta, Activating transcription factor 5, Activating transcription factor X, AFTA, ATF 5, ATF 7, ATF7, ATFX, BZIP protein ATF7, cAMP dependent transcription factor ATF 5, cAMP dependent transcription factor ATF5, Cyclic AMP dependent transcription factor ATF 5, Cyclic AMP dependent transcription factor ATF5, FLJ34666, HMFN0395, MGC102397, NAP1, NR3 associated protein, ODA 10, Transcription factor ATFx, Transcription factor like protein ODA 10, Transcription factor like protein ODA10, ATF5_HUMAN.

Background: Eukaryotic gene transcription is regulated by sequence-specific transcription factors that bind modular cis acting promoter and enhancer elements. The ATF/CREB transcription factor family binds the palindromic cAMP response element (CRE) octanucleotide TGACGTCA. The best characterized members of this gene family include CREB-1, CREB-2 (also designated ATF-4), CRE-BPa, LZIP (also designated CREB3 and Luman), CREM-1, CREM-2, ATF-1, ATF-2, ATF-3, ATF-5, ATF-6 and ATF-7. This family of proteins contain highly divergent N-terminal domains, but share a C-terminal leucine zipper for dimerization and DNA binding. ATF-5 (ATFx), which can localize to the cytoplasm or the nucleus, binds DNA as a dimer. It interacts with CCND3 and PTP4A1.

Gene ID: 22809

Pathways: Myometrial Relaxation and Contraction