STK33 antibody (AA 101-200) (AbBy Fluor® 488)

Catalog No. ABIN1695530

The Rabbit Polyclonal anti-STK33 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect STK33 in samples from Human.

Quick Overview for STK33 antibody (AA 101-200) (AbBy Fluor® 488) (ABIN1695530)

Target: STK33 (serine/threonine Kinase 33 (STK33))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK33 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-STK33 Antibody (AbBy Fluor® 488)

Binding Specificity: AA 101-200

Predicted Reactivity: Human,Mouse,Rat,Dog,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human STK33

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for STK33

Target: STK33 (serine/threonine Kinase 33 (STK33))

Alternative Name: STK33

Background:

Synonyms: Hypothetical protein FLJ35932, Serine threonine kinase 33, Serine/threonine kinase 33, Serine/threonine protein kinase 33, Serine/threonine-protein kinase 33, STK 33, Stk33, STK33_HUMAN.

Background: The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. STK33 (serine/threonine kinase 33) is a 514 amino acid protein that belongs to the CaMK (calcium/calmodulin dependent kinase) subfamily of structurally related serine/threonine kinases. Widely expressed at low levels with predominant expression in testis, lung, retina and fetal organs such as brain, heart and spinal cord, STK33 contains one protein kinase domain and functions as a Ser/Thr protein kinase with a possible role in spermatogenesis. The gene encoding STK33 lies within a region on chromosome 11 that has been associated with a variety of defects, including Long QT syndrome, T-cell leukemia, Beckwith-Wiedemann syndrome, Usher syndrome 1C and various other malignancies.

Gene ID: 65975