GK2 antibody (AA 101-200) (AbBy Fluor® 488)

Catalog No. ABIN1695860

The Rabbit Polyclonal anti-GK2 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect GK2 in samples from Human and Rat.

Quick Overview for GK2 antibody (AA 101-200) (AbBy Fluor® 488) (ABIN1695860)

Target: GK2 (Glycerol Kinase 2 (GK2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GK2 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-GK2 Antibody (AbBy Fluor® 488)

Binding Specificity: AA 101-200

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GK2/Glycerol kinase 2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GK2

Target: GK2 (Glycerol Kinase 2 (GK2))

Alternative Name: GK2/Glycerol kinase 2

Background:

Synonyms: ATP:glycerol 3 phosphotransferase, EC 2.7.1.30, GK 2, GK, GKP2, GKTA, Glycerokinase, Glycerol kinase 2, Glycerol kinase testis specic 2, GLPK2_HUMAN.

Background: GK2 is a 553 amino acid protein that belongs to the FGGY kinase family and is involved in the pathway of glycerol degradation. Localized to the outer membrane of the mitochondrion and expressed at high levels in testis, GK2 functions to catalyze the ATP-dependent conversion of glycerol to glycerol 3-phosphate. Via its catalytic activity, GK2 plays an essential role in the regulation of glycerol uptake and metabolism. The gene encoding GK2 maps to chromosome 4, which encodes nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

Gene ID: 2712