GNPDA2 antibody (AA 101-200) (AbBy Fluor® 488)

Catalog No. ABIN1695872

The Rabbit Polyclonal anti-GNPDA2 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect GNPDA2 in samples from Mouse and Rat.

Quick Overview for GNPDA2 antibody (AA 101-200) (AbBy Fluor® 488) (ABIN1695872)

Target: GNPDA2 (Glucosamine-6-Phosphate Deaminase 2 (GNPDA2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNPDA2 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-GNPDA2 Antibody (AbBy Fluor® 488)

Binding Specificity: AA 101-200

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GNPDA2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GNPDA2

Target: GNPDA2 (Glucosamine-6-Phosphate Deaminase 2 (GNPDA2))

Alternative Name: GNPDA2

Background:

Synonyms: GlcN6P deaminase 2, Glucosamine 6 phosphate deaminase 2, Glucosamine 6 phosphate isomerase 2, Glucosamine 6 phosphate isomerase SB52, Glucosamine-6-phosphate deaminase 2, Glucosamine-6-phosphate isomerase 2, Glucosamine-6-phosphate isomerase SB52, GNP2, GNPDA 2, Gnpda2, GNPI2_HUMAN, SB52.

Background: During fertilization in mammals, the sperm activates the egg by causing an increase in the level of free cytoplasmic calcium concentration. This increased calcium concentration induces a characteristic series of oscillations that trigger egg activation and early embryo development. A hamster protein named oscillin is thought to be involved in this pathway. The enzyme glucosamine-6-phosphate isomerase (GNPI) or deaminase (GNPDA1) and the related protein GNPDA2 are the human homologs of hamster oscillin. GNPDA1 and GNPDA2 catalyze the conversion of GNP to fructose-6-phosphate and ammonia. Both proteins exist as homohexamers and are ubiquitously expressed with highest expression in testis, ovary and heart. Three isoforms of GNPDA2 are expressed due to alternative splicing events.

Gene ID: 132789