Biliverdin Reductase antibody (AA 161-260) (AbBy Fluor® 555)

Catalog No. ABIN1697813

The Rabbit Polyclonal anti-Biliverdin Reductase antibody has been validated for FACS, IF (cc) and IF (p). It is suitable to detect Biliverdin Reductase in samples from Human and Rat.

Quick Overview for Biliverdin Reductase antibody (AA 161-260) (AbBy Fluor® 555) (ABIN1697813)

Target: Biliverdin Reductase (BLVRA) (Biliverdin Reductase A (BLVRA))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Biliverdin Reductase antibody is conjugated to AbBy Fluor® 555

Application: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Biliverdin Reductase Antibody (AbBy Fluor® 555)

Binding Specificity: AA 161-260

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BLVRA/Biliverdin Reductase

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Biliverdin Reductase

Target: Biliverdin Reductase (BLVRA) (Biliverdin Reductase A (BLVRA))

Alternative Name: BLVRA/Biliverdin Reductase

Background:

Synonyms: Biliverdin IX alpha reductase, Biliverdin reductase A, BLVR A, BLVR, BLVRA, BVR A, BVR, BVRA, zinc-metalloprotein, BIEA_HUMAN.

Background: In human liver cytosolic fractions, four forms of biliverdin reductase have been identified, including two biliverdin-IX Beta reductases and two biliverdin-IX Alpha reductases, designated isozymes I and II and isozymes III and IV, respectively. Biliverdin reductase A (BLVRA), also designated biliverdin-IX Alpha-reductase, belongs to the GFO/iIDH/MocA family and the biliverdin reductase subfamily. The gene that encodes this cytoplasmic protein maps to chromosome 7p14-cen. BLVRA reduces biliverdin IX ?(the ?methene bridge of the open tetrapyrrole) to bilirubin with the concomitant oxidation of an NADH or NADPH cofactor (bilirubin + NADP+ = biliverdin + NADPH). BLVRA is expressed primarily in liver.

Gene ID: 644