IGLL1 antibody (AA 151-213) (AbBy Fluor® 647)

Catalog No. ABIN1698236

The Rabbit Polyclonal anti-IGLL1 antibody has been validated for WB, IF (cc), IF (p). It is suitable to detect IGLL1 in samples from Mouse.

Quick Overview for IGLL1 antibody (AA 151-213) (AbBy Fluor® 647) (ABIN1698236)

Target: IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGLL1 antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-IGLL1 Antibody (AbBy Fluor® 647)

Binding Specificity: AA 151-213

Cross-Reactivity: Mouse

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IGLL1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for IGLL1

Target: IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))

Alternative Name: Igll1

Background:

Synonyms: 14.1, AGM2, CD179 antigen-like family member B, CD179B, CD179b antigen, Ig lambda 5, Ig lambda-5, IGL1, IGL5, IGLJ14.1, IGLL, Igll1, IGLL1_HUMAN, IGO, IGVPB, Immunoglobulin lambda like polypeptide 1 precursor, Immunoglobulin lambda-like polypeptide 1, Immunoglobulin omega polypeptide, Immunoglobulin omega polypeptide chain, Immunoglobulin related protein 14.1, Immunoglobulin-related protein 14.1, Lambda5, Pre B lymphocyte specic protein 2, VPREB2.

Background: The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Pathways: Regulation of Cell Size