FOXP3 antibody (AA 331-431) (AbBy Fluor® 647)

Catalog No. ABIN1699601

The Rabbit Polyclonal anti-FOXP3 antibody has been validated for WB, FACS, IF (p) and IF (cc). It is suitable to detect FOXP3 in samples from Human, Mouse and Rat.

Quick Overview for FOXP3 antibody (AA 331-431) (AbBy Fluor® 647) (ABIN1699601)

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXP3 antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-FOXP3 Antibody (AbBy Fluor® 647)

Binding Specificity: AA 331-431

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FoxP3

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FOXP3

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Alternative Name: FoxP3

Background:

Synonyms: AIID, AIID, DIETER, DIETER, Forkhead box P3, Forkhead box protein P3, foxp3, foxp3, FOXP3_HUMAN, FOXP3delta7, Immune dysregulation polyendocrinopathy enteropathy X linked, Immunodeficiency polyendocrinopathy enteropathy X linked, IPEX, IPEX, JM2, JM2, MGC141961, MGC141963, OTTHUMP00000025832, OTTHUMP00000025833, OTTHUMP00000226737, PIDX, PIDX, SCURFIN, SCURFIN, XPID, XPID.

Background: The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation