FAM217A antibody (AA 301-400) (Biotin)

Catalog No. ABIN1699922

The Rabbit Polyclonal anti-FAM217A antibody has been validated for WB, ELISA, IHC (fro) and IHC (p). It is suitable to detect FAM217A in samples from Human.

Quick Overview for FAM217A antibody (AA 301-400) (Biotin) (ABIN1699922)

Target: FAM217A (Family with Sequence Similarity 217, Member A (FAM217A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM217A antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FAM217A Antibody (Biotin)

Binding Specificity: AA 301-400

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C6orf146

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for FAM217A

Target: FAM217A (Family with Sequence Similarity 217, Member A (FAM217A))

Alternative Name: C6orf146

Background:

Synonyms: Chromosome 6 open reading frame 146, Hypothetical protein LOC222826, MGC43581, Uncharacterized protein C6orf146.

Background: Making up nearly 6 % of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf146 gene product has been provisionally designated C6orf146 pending further characterization.

Gene ID: 222826