C9orf96 antibody (AA 101-200) (Biotin)

Catalog No. ABIN1699955

The Rabbit Polyclonal anti-C9orf96 antibody is suitable to detect C9orf96 in samples from Human. It has been validated for ELISA, IHC (fro) and IHC (p).

Quick Overview for C9orf96 antibody (AA 101-200) (Biotin) (ABIN1699955)

Target: C9orf96 (Chromosome 9 Open Reading Frame 96 (C9orf96))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C9orf96 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-C9orf96 Antibody (Biotin)

Binding Specificity: AA 101-200

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C9orf96

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for C9orf96

Target: C9orf96 (Chromosome 9 Open Reading Frame 96 (C9orf96))

Alternative Name: C9orf96

Background:

Synonyms: Chromosome 9 open reading frame 96, Hypothetical protein LOC169436, MGC43306, Protein kinase like protein SgK071, SGK 071, SGK071, SGK71_HUMAN.

Background: C9orf96, also known as Protein kinase-like protein SgK071, is a 680 amino acid protein that belongs to the Ser/Thr protein kinase family of the protein kinase superfamily. There are three isoforms of C9orf96 that are produced as a result of alternative splicing events. The gene encoding C9orf96 maps to human chromosome 9, which consists of about 145 million bases and 4 % of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.

Gene ID: 169436