GS28 antibody (AA 151-250) (Biotin)

Catalog No. ABIN1700320

This Rabbit Polyclonal antibody specifically detects GS28 in WB, ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Mouse and Rat.

Quick Overview for GS28 antibody (AA 151-250) (Biotin) (ABIN1700320)

Target: GS28 (GOSR1) (Golgi SNAP Receptor Complex Member 1 (GOSR1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GS28 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GS28 Antibody (Biotin)

Binding Specificity: AA 151-250

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GOSR1/GS28

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for GS28

Target: GS28 (GOSR1) (Golgi SNAP Receptor Complex Member 1 (GOSR1))

Alternative Name: GOSR1/GS28

Background:

Synonyms: P28, GS28, GOS28, GOLIM2, GOS-28, GOS28/P28, Golgi SNAP receptor complex member 1, 28 kDa Golgi SNARE protein, 28 kDa cis-Golgi SNARE p28, GOSR1

Background: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.

Gene ID: 9527

UniProt: O95249