CSNK1A1 antibody (pTyr294) (Biotin)

Catalog No. ABIN1700478

This anti-CSNK1A1 antibody is a Rabbit Polyclonal antibody detecting CSNK1A1 in WB, ELISA, IHC (p) and IHC (fro). Suitable for Human and Rat.

Quick Overview for CSNK1A1 antibody (pTyr294) (Biotin) (ABIN1700478)

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSNK1A1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CSNK1A1 Antibody (Biotin)

Binding Specificity: pTyr294

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Sheep,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Casein Kinase 1 alpha around the phosphorylation site of Tyr294

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CSNK1A1

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Background:

Synonyms: Casein Kinase 1 alpha phospho Y294, p-CK1A phospho Y294, Casein kinase 1 alpha 1, Casein kinase I isoform alpha, CK1, CK1A, CKI alpha, CKI-alpha, CKIa, Clock regulator kinase, Csnk1a1, Down regulated in lung cancer, HLCDGP1, KC1A_HUMAN, PRO2975.

Background: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis.

Gene ID: 1452

Pathways: WNT Signaling, Hedgehog Signaling