RTF1 antibody (AA 231-350) (Biotin)

Catalog No. ABIN1700566

This Rabbit Polyclonal antibody specifically detects RTF1 in ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for RTF1 antibody (AA 231-350) (Biotin) (ABIN1700566)

Target: RTF1 (RNA polymerase-associated protein RTF1 homolog (RTF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RTF1 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-RTF1 Antibody (Biotin)

Binding Specificity: AA 231-350

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RTF1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for RTF1

Target: RTF1 (RNA polymerase-associated protein RTF1 homolog (RTF1))

Alternative Name: RTF1

Background:

Synonyms: CDG1N, GTL 7, GTL7, KIAA0252, Ortholog of mouse gene trap locus 7, RNA polymerase associated protein RTF1 homolog, RNA polymerase-associated protein RTF1 homolog, RTF 1, RTF1, Rtf1 Paf1/RNA polymerase II complex component homolog, RTF1_HUMAN, rtf1L, YGL244W,

Background: RTF1 is the the major histocompatibility complex (MHC) in the rat which contains genes that code for two class II histocompatibility antigens. RT1-B is an antigen of the RT1 complex. It is a protein dimer consisting of an alpha and beta glycoprotein chain and is homologous to I-A and I-E genes, respectively, in the H-2 complex of the mouse. MHC Class II antigens are useful in studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these also stain stromal cells in the thymus.

Gene ID: 23168

Pathways: Stem Cell Maintenance