FAHD1 antibody (AA 101-200) (Biotin)

Catalog No. ABIN1700655

This anti-FAHD1 antibody is a Rabbit Polyclonal antibody detecting FAHD1 in WB, ELISA, IHC (fro) and IHC (p). Suitable for Human.

Quick Overview for FAHD1 antibody (AA 101-200) (Biotin) (ABIN1700655)

Target: FAHD1 (Fumarylacetoacetate Hydrolase Domain Containing 1 (FAHD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAHD1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FAHD1 Antibody (Biotin)

Binding Specificity: AA 101-200

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAHD1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for FAHD1

Target: FAHD1 (Fumarylacetoacetate Hydrolase Domain Containing 1 (FAHD1))

Alternative Name: FAHD1

Background:

Synonyms: Acylpyruvase FAHD1, C16orf36, Chromosome 16 open reading frame 36, DKFZP566J2046, FAHD1, FAHD1_HUMAN, Fumarylacetoacetate hydrolase domain containing protein 1, Fumarylacetoacetate hydrolase domain-containing protein 1, MGC74876, mitochondrial, YISK like, YISK like/RJD15, YisK-like protein, YISKL.

Background: FAHD1 is a 224 amino acid protein belonging to the FAH family. Present as a homodimer, FAHD1 is thought to have hydrolase activity and uses magnesium and calcium as cofactors. The gene that encodes FAHD1 maps to human chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, making up nearly 3 % of human cellular DNA. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.

Gene ID: 81889