RBM15 antibody (AA 151-250) (Biotin)

Catalog No. ABIN1700724

This anti-RBM15 antibody is a Rabbit Polyclonal antibody detecting RBM15 in ELISA, IHC (p) and IHC (fro). Suitable for Human.

Quick Overview for RBM15 antibody (AA 151-250) (Biotin) (ABIN1700724)

Target: RBM15 (RNA Binding Motif Protein 15 (RBM15))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBM15 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-RBM15 Antibody (Biotin)

Binding Specificity: AA 151-250

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RBM15

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for RBM15

Target: RBM15 (RNA Binding Motif Protein 15 (RBM15))

Alternative Name: RBM15/SPEN

Background:

Synonyms: One twenty two protein, OTT, OTT1, SPEN, RNA binding mot protein 15, RBM15_HUMAN.

Background: RBM15 is a 977 amino acid protein that localizes to the nucleus and contains one SPOC domain and three RRM domains. Expressed as multiple alternatively spliced isoforms, RBM15 interacts with Epstein-Barr (EBV) viral proteins and is thought to be involved in the regulation of Hox genes, possibly via interactions with RNA and spliceosome components. RBM15 is subject to post-translational phosphorylation, probably by ATM or ATR. Chromosomal aberrations involving the RBM15 gene, which localizes to human chromosome 1, may be associated with the development of acute megakaryoblastic leukemia.