CAPRIN2 antibody (AA 101-200) (Biotin)

Catalog No. ABIN1700777

The Rabbit Polyclonal anti-CAPRIN2 antibody has been validated for WB, ELISA, IHC (fro) and IHC (p). It is suitable to detect CAPRIN2 in samples from Human, Mouse and Rat.

Quick Overview for CAPRIN2 antibody (AA 101-200) (Biotin) (ABIN1700777)

Target: CAPRIN2 (Caprin Family Member 2 (CAPRIN2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAPRIN2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CAPRIN2 Antibody (Biotin)

Binding Specificity: AA 101-200

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CAPRIN2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CAPRIN2

Target: CAPRIN2 (Caprin Family Member 2 (CAPRIN2))

Alternative Name: CAPRIN2

Background:

Synonyms: C1q domain-containing protein 1, C1QDC1, CAPR2_HUMAN, Caprin family member 2, Caprin-2, caprin2, Cytoplasmic activation/proliferation-associated protein 2, EEG 1, EEG1, Gastric cancer multidrug resistance-associated protein, KIAA1873, Protein EEG-1, RNA granule protein 140, RNG140.

Background: Caprin2 is 1127 amino acid highly conserved protein that is ubiquitously expressed with highest levels of expression in brain and spleen. Caprin2 stabilizes cytosolic _-catenin and enhances LEF-1 dependent reporter gene activity as well as the expression of Wnt target genes in mammalian cells. Caprin2 promotes LRP5/6 phosphorylation by GSK-3 and enhances the interaction between Axin and LRP5/6. It is suggested that Caprin2 functions as a proapoptotic inhibitor of the cell cycle. Nine isoforms of Caprin2 exist due to alternative splicing events.

Gene ID: 65981

UniProt: Q6IMN6