FLNB antibody (AA 1551-1650) (Biotin)

Catalog No. ABIN1701034

This Rabbit Polyclonal antibody specifically detects FLNB in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for FLNB antibody (AA 1551-1650) (Biotin) (ABIN1701034)

Target: FLNB (Filamin B, beta (FLNB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLNB antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-FLNB Antibody (Biotin)

Binding Specificity: AA 1551-1650

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FLNB/Filamin 3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for FLNB

Target: FLNB (Filamin B, beta (FLNB))

Alternative Name: FLNB/Filamin 3

Background:

Synonyms: ABP 278, ABP 280 homolog, ABP-278, ABP-280 homolog, ABP278, Actin binding like protein, Actin binding protein 278, Actin-binding-like protein, AOI, Beta filamin, Beta-filamin, DKFZp686A1668, DKFZp686O033, Fh1, Filamin 1 actin binding protein 280 like, Filamin 3, Filamin B, Filamin B beta actin binding protein 278, Filamin homolog 1, Filamin-3, Filamin-B, FLN B, FLN-B, FLN1L, FLN3, FLNB, FLNB_HUMAN, LRS1, SCT, TABP, TAP, Thyroid autoantigen, Truncated ABP, Truncated actin binding protein, Truncated actin-binding protein.

Background: This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3, boomerang dysplasia, autosomal dominant Larsen syndrome, and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Nov 2009].

Gene ID: 2317

Pathways: Maintenance of Protein Location