ACAA1 antibody (AA 231-330) (Biotin)

Catalog No. ABIN1701086

The Rabbit Polyclonal anti-ACAA1 antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect ACAA1 in samples from Human.

Quick Overview for ACAA1 antibody (AA 231-330) (Biotin) (ABIN1701086)

Target: ACAA1 (Acetyl-CoA Acyltransferase 1 (ACAA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACAA1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ACAA1 Antibody (Biotin)

Binding Specificity: AA 231-330

Predicted Reactivity: Human,Mouse,Rat,Dog,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ABLIM3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for ACAA1

Target: ACAA1 (Acetyl-CoA Acyltransferase 1 (ACAA1))

Alternative Name: ACAA1

Background:

Synonyms: 3 ketoacyl CoA thiolase peroxisomal, 3-ketoacyl-CoA thiolase, ACAA, ACAA1, Acetyl CoA acyltransferase 1, Acetyl Coenzyme A acyltransferase 1, Acetyl-CoA acyltransferase, Acetyl-Coenzyme A acyltransferase 1 peroxisomal 3 oxoacyl Coenzyme A, Beta ketothiolase, Beta-ketothiolase, Peroxisomal 3 oxoacyl CoA thiolase, Peroxisomal 3 oxoacyl Coenzyme A thiolase, Peroxisomal 3-oxoacyl-CoA thiolase, peroxisomal, PTHIO, THIK_HUMAN, THIO.

Background: ACAA1 is a 424 amino acid member of the thiolase family of enzymes and is involved in lipid metabolism. Localized to the peroxisome, ACAA1 catalyzes the conversion of acyl-CoA and acetyl-CoA to 3-oxoacyl-CoA in the fatty acid oxidation pathway. ACAA1 shows high enzymatic activity in liver, kidney, intestine and white adipose tissue in rats, where it exists as two types, namely type A and type B. Human ACAA1 shares 86 % amino acid identity with its rat counterpart, suggesting a conserved function for ACAA1 among different species.

Gene ID: 30

Pathways: Monocarboxylic Acid Catabolic Process