PD-L1 antibody (AA 64-160) (Biotin)

Catalog No. ABIN1701548

The Rabbit Polyclonal anti-PD-L1 antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect PD-L1 in samples from Human, Mouse and Rat.

Quick Overview for PD-L1 antibody (AA 64-160) (Biotin) (ABIN1701548)

Target: PD-L1 (CD274 (PD-L1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PD-L1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PD-L1 Antibody (Biotin)

Binding Specificity: AA 64-160

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD274

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for PD-L1

Target: PD-L1 (CD274 (PD-L1))

Alternative Name: CD274

Background:

Synonyms: B7-H, B7H1, PDL1, PD-L1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1, PDCD1 ligand 1, Programmed death ligand 1, B7 homolog 1, B7-H1, CD274

Background: Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.

Gene ID: 29126

UniProt: Q9NZQ7

Pathways: Cancer Immune Checkpoints