H2BFWT antibody (AA 1-100) (Cy3)

Catalog No. ABIN1701835

This Rabbit Polyclonal antibody specifically detects H2BFWT in WB, IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for H2BFWT antibody (AA 1-100) (Cy3) (ABIN1701835)

Target: H2BFWT (H2B Histone Family, Member W, Testis-Specific (H2BFWT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H2BFWT antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-H2BFWT Antibody (Cy3)

Binding Specificity: AA 1-100

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human H2BFWT

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for H2BFWT

Target: H2BFWT (H2B Histone Family, Member W, Testis-Specific (H2BFWT))

Alternative Name: H2bfwt

Background:

Synonyms: H2B histone family member W testis-specic, H2BFWT, H2BWT_HUMAN, Histone H2B type W-T.

Background: H2BFWT (H2B histone family member W testis-specific) is a 175 amino acid nuclear membrane histone that belongs to the histone H2B family. In contrast to most H2B histones, H2BFWT does not contain the conserved C-terminal residue involved in monoubiquitination, but is structurally indistinguishable from conventional H2B histones. Also varying from other H2B histones, H2BFWT does not participate in the recruitment of chromosome condensation factors or in the assembly of mitotic chromsomes. Expressed in testis, H2BFWT is present in sperm cells and may be essential to telomere function.

Gene ID: 158983