C8ORF58 antibody (AA 251-365) (Cy3)

Catalog No. ABIN1702042

This Rabbit Polyclonal antibody specifically detects C8ORF58 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human and Rat.

Quick Overview for C8ORF58 antibody (AA 251-365) (Cy3) (ABIN1702042)

Target: C8ORF58 (Chromosome 8 Open Reading Frame 58 (C8ORF58))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C8ORF58 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-C8ORF58 Antibody (Cy3)

Binding Specificity: AA 251-365

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C8orf58

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for C8ORF58

Target: C8ORF58 (Chromosome 8 Open Reading Frame 58 (C8ORF58))

Alternative Name: C8orf58

Background:

Synonyms: C8orf58, CH058_HUMAN, Chromosome 8 open reading frame 58, Uncharacterized protein C8orf58.

Background: C8orf58 (chromosome 8 open reading frame 58) is a 365 amino acid protein that exists as two alternatively spliced isoforms, which are encoded by a gene that maps to human chromosome 8p21. Consisting of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.

Gene ID: 541565