ZBTB46 antibody (Cy3)

Catalog No. ABIN1702289

The Rabbit Polyclonal anti-ZBTB46 antibody has been validated for WB. It is suitable to detect ZBTB46 in samples from Human, Mouse and Rat.

Quick Overview for ZBTB46 antibody (Cy3) (ABIN1702289)

Target: ZBTB46 (ZNF340) (Zinc Finger Protein 340 (ZNF340))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBTB46 antibody is conjugated to Cy3

Application: Western Blotting (WB)

Product Details anti-ZBTB46 Antibody (Cy3)

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZBTB46/BTBD4

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ZBTB46

Target: ZBTB46 (ZNF340) (Zinc Finger Protein 340 (ZNF340))

Alternative Name: Zbtb46/Btbd4

Background:

Synonyms: BTB/POZ domain containing protein 4, BTBD4, RINZF, Zinc finger and BTB domain containing 46, Zinc finger and BTB domain containing protein 46, Zinc finger protein 340, ZNF340, ZBT46_HUMAN.

Background: BTBD4 is a 589 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation.

Gene ID: 140685