TCTN3 antibody (AA 201-300) (Cy3)

Catalog No. ABIN1702382

The Rabbit Polyclonal anti-TCTN3 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect TCTN3 in samples from Human.

Quick Overview for TCTN3 antibody (AA 201-300) (Cy3) (ABIN1702382)

Target: TCTN3 (Tectonic Family Member 3 (TCTN3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCTN3 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-TCTN3 Antibody (Cy3)

Binding Specificity: AA 201-300

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TCTN3/TECT3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TCTN3

Target: TCTN3 (Tectonic Family Member 3 (TCTN3))

Alternative Name: TCTN3/TECT3

Background:

Synonyms: C10orf61, Chromosome 10 open reading frame 61, DKFZP564D116, TCTN3, TECT3_HUMAN, Tectonic 3, Tectonic 3 precursor, Tectonic family member 3, Tectonic-3.

Background: Tect3 is a 607 amino acid single-pass type I membrane protein that belongs to the tectonic family and exists as four alternatively spliced isoforms. Tect3 interacts with MKS1 and may be involved in apoptosis regulation. The gene that encodes Tect3 contains approximately 31,560 bases and maps to human chromosome 10q24.1. Spanning nearly 135 million base pairs and encoding nearly 1,200 genes, chromosome 10 makes up approximately 4.5 % of the human genome. Several protein-coding genes, including those that encode chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman?s syndrome, Cowden syndrome, Cockayne syndrome, multiple endocrine neoplasia type 2 and porphyria. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10.

Gene ID: 26123