ARID3B antibody (AA 251-350) (Cy3)

Catalog No. ABIN1702730

The Rabbit Polyclonal anti-ARID3B antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect ARID3B in samples from Human.

Quick Overview for ARID3B antibody (AA 251-350) (Cy3) (ABIN1702730)

Target: ARID3B (AT Rich Interactive Domain 3B (BRIGHT-Like) (ARID3B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARID3B antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-ARID3B Antibody (Cy3)

Binding Specificity: AA 251-350

Predicted Reactivity: Human,Mouse,Rat,Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BDP/ARID3B

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ARID3B

Target: ARID3B (AT Rich Interactive Domain 3B (BRIGHT-Like) (ARID3B))

Alternative Name: BDP/ARID3B

Background:

Synonyms: ARI3B_HUMAN, ARID domain containing protein 3B, ARID domain-containing protein 3B, Arid3b, AT rich interactive domain 3B BRIGHT like, AT rich interactive domain containing protein 3B, AT-rich interactive domain-containing protein 3B, Bright and dead ringer gene product homologous protein Bdp, Bright and dead ringer protein, Bright like, Bright-like protein, Brightlike, DRIL2.

Background: ARID3B represents a member of a unique family of DNA-binding proteins that have roles in cell lineage gene regulation, cell cycle control, embryonic patterning and transcriptional regulation. ARID3B localizes to the nucleus and contains an AT-rich interactive domain (ARID) which has DNA-binding capabilities. Functioning as a transcription factor, ARID3B associates in a heterodimer with the related protein ARID3A and is believed to play an important role in neural crest survival during embryogenesis. In addition, ARID3B may participate in malignant transformation and neuroblastoma growth, suggesting a possible use of ARID3B as a tumor marker for neuroblastoma.

Gene ID: 10620