STRA6 antibody (AA 151-250) (Cy3)

Catalog No. ABIN1702790

The Rabbit Polyclonal anti-STRA6 antibody has been validated for IF (cc) and IF (p). It is suitable to detect STRA6 in samples from Human.

Quick Overview for STRA6 antibody (AA 151-250) (Cy3) (ABIN1702790)

Target: STRA6 (Stimulated By Retinoic Acid 6 (STRA6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STRA6 antibody is conjugated to Cy3

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-STRA6 Antibody (Cy3)

Binding Specificity: AA 151-250

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human STRA6

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for STRA6

Target: STRA6 (Stimulated By Retinoic Acid 6 (STRA6))

Alternative Name: STRA6

Background:

Synonyms: Stimulated by retinoic acid gene 6 protein homolog, STRA6_HUMAN.

Background: STRA6 is a 667 amino acid, multi-pass cell membrane protein. Stra6 functions as a cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4). Ultimately increasing cellular retinol uptake from the retinol-RBP complex, Stra6 removes retinol from RBP/RPB4 and transports it across the plasma membrane, where it is metabolized. Stra6 is broadly expressed, with 4 named isoforms that exist as a result of alternative splicing events. Mutations in the gene encoding Stra6 cause Matthew-Wood Syndrome, also known as Spear Syndrome. This syndrome is characterized by anophtalmia, mild facial dysmorphism and malformations of the heart, lung and diaphragm. The Stra6 gene maps to chromosome 15q24.1.

Gene ID: 64220

UniProt: Q9BX79

Pathways: Feeding Behaviour