FOXN2 antibody (AA 51-150) (Cy3)

Catalog No. ABIN1702925

The Rabbit Polyclonal anti-FOXN2 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect FOXN2 in samples from Mouse.

Quick Overview for FOXN2 antibody (AA 51-150) (Cy3) (ABIN1702925)

Target: FOXN2 (Forkhead Box N2 (FOXN2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXN2 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-FOXN2 Antibody (Cy3)

Binding Specificity: AA 51-150

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FOXN2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FOXN2

Target: FOXN2 (Forkhead Box N2 (FOXN2))

Alternative Name: FOXN2

Background:

Synonyms: 3230402J05Rik, 6030465J18Rik, Fkh19, Forkhead box N2, Forkhead box protein N2, Foxn1, foxn2, FOXN2_HUMAN, HTLF, Human T-cell leukemia virus enhancer factor.

Background: The forkhead domain-containing gene family (Fox) comprises over 20 members in mammals and is defined by a conserved 110 amino-acid motif containing a winged helix structure DNA-binding domain. The members of this gene family have been implicated as key regulators of embryogenesis, cell cycling, cell lineage restriction and cancer. As such, FOXN2 contains a domain with homology to the forkhead DNA binding domain. FOXN2, or Human T-cell leukemia virus enhancer factor, is a 341 amino acid protein mapping to human gene FOXN2, which has been localized to human chromosome 2p16-p22. This protein, encoded by a 1239-bp cDNA isolated from the Jurkat cDNA library, is capable of binding to a region of the human T-cell leukemia virus long terminal repeat (HTLV-I LTR) located between amino acids 155 and 117. This purine-rich region is important in the regulation of gene expression by the Ets family of transcription factors. FOXN2 is a unique cellular gene that may function in the transcriptional regulation of HTLV-I LTR.

Gene ID: 3344