FBLN4 antibody (AA 331-443) (Cy3)

Catalog No. ABIN1703047

This Rabbit Polyclonal antibody specifically detects FBLN4 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for FBLN4 antibody (AA 331-443) (Cy3) (ABIN1703047)

Target: FBLN4 (Fibulin 4 (FBLN4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBLN4 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-FBLN4 Antibody (Cy3)

Binding Specificity: AA 331-443

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EFEMP2/Fibulin 4

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FBLN4

Target: FBLN4 (Fibulin 4 (FBLN4))

Alternative Name: EFEMP2/Fibulin 4

Background:

Synonyms: EFEMP2, EGF containing fibulin like extracellular matrix protein 2, EGF-containing fibulin-like extracellular matrix protein 2, FBLN 4, FBLN4, FBLN4_HUMAN, FIBL 4, FIBL-4, FIBL4, Fibulin4, Fibulin-4, MBP 1, MBP1, Mutant p53 binding protein 1, Protein UPH1, UPH 1, UPH1, UPH1 protein.

Background: Fibulin proteins contribute to normal development of elastic fiber systems in various types of organs that require elasticity, such as vasculature, lung and skin. Fibulin-4, also known as EFEMP2 (EGF-containing fibulin-like extracellular matrix protein 2), MBP1 or UPH1 is a 443 amino acid secreted protein that contains six EGF-like calcium-binding domains and belongs to the fibulin family. Expressed ubiquitously with highest expression in heart, Fibulin-4 is essential for connective tissue development and elastic fiber formation, and may also play an important role in vascular patterning and collagen biosynthesis. Defects in the gene encoding Fibulin-4 are associated with autosomal recessive cutis laxa type I (CL type I), a connective tissue disorder that is inherited in both an autosomal dominant and an autosomal recessive manner and is characterized by inelastic tissue in all affected areas of the body.

Gene ID: 30008