FOXP3 antibody (AA 331-431) (Cy5)

Catalog No. ABIN1705038

This anti-FOXP3 antibody is a Rabbit Polyclonal antibody detecting FOXP3 in WB, FACS, IF (p) and IF (cc). Suitable for Human, Mouse and Rat.

Quick Overview for FOXP3 antibody (AA 331-431) (Cy5) (ABIN1705038)

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXP3 antibody is conjugated to Cy5

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-FOXP3 Antibody (Cy5)

Binding Specificity: AA 331-431

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FoxP3

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FOXP3

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Alternative Name: FoxP3

Background:

Synonyms: AIID, AIID, DIETER, DIETER, Forkhead box P3, Forkhead box protein P3, foxp3, foxp3, FOXP3_HUMAN, FOXP3delta7, Immune dysregulation polyendocrinopathy enteropathy X linked, Immunodeficiency polyendocrinopathy enteropathy X linked, IPEX, IPEX, JM2, JM2, MGC141961, MGC141963, OTTHUMP00000025832, OTTHUMP00000025833, OTTHUMP00000226737, PIDX, PIDX, SCURFIN, SCURFIN, XPID, XPID.

Background: The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation