OVOL2 antibody (AA 75-180) (Cy5)

Catalog No. ABIN1705168

This Rabbit Polyclonal antibody specifically detects OVOL2 in WB, IF (cc) and IF (p). It exhibits reactivity toward Mouse and Rat.

Quick Overview for OVOL2 antibody (AA 75-180) (Cy5) (ABIN1705168)

Target: OVOL2 (Ovo-Like 2 (OVOL2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OVOL2 antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-OVOL2 Antibody (Cy5)

Binding Specificity: AA 75-180

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human OVOL2/ZNF339

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for OVOL2

Target: OVOL2 (Ovo-Like 2 (OVOL2))

Alternative Name: OVOL2/ZNF339

Background:

Synonyms: bA504H3.3, EUROIMAGE566589, hOvo 2, hOvo2, Ovo like 2 Drosophila, Ovo like 2, OVOL 2, Transcription factor Ovo like 2, Zinc finger protein 339, ZNF 339, ZNF339, OVOL2_HUMAN.

Background: The Ovo family of zinc-finger transcription factors encode evolutionarily conserved genes including those from Caenorhabditis elegans, Drosophila melanogaster, mouse and human. Members of the Ovo family include Ovol1 and Ovol2. Ovol1 acts as a transcriptional repressor by interacting with key developmental signaling pathways such as Wnt and TGF-/BMP. Specifically, Ovol1 represses c-Myc and Id2 genes and establishes a balance between proliferation and differentiation of progenitor cells. Deletion of Ovol1 in mice leads to germ cell degeneration and defective sperm production in adult males. Ovol1 has also been shown to repress itself as well as Ovol2, which is thought to regulate neural development and vascular angiogenesis during embryogenesis.

Gene ID: 58495

Pathways: Tube Formation