TSPAN32 antibody (AA 101-200) (Cy5.5)

Catalog No. ABIN1705499

The Rabbit Polyclonal anti-TSPAN32 antibody has been validated for IF (cc) and IF (p). It is suitable to detect TSPAN32 in samples from Human and Mouse.

Quick Overview for TSPAN32 antibody (AA 101-200) (Cy5.5) (ABIN1705499)

Target: TSPAN32 (Tetraspanin 32 (TSPAN32))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSPAN32 antibody is conjugated to Cy5.5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-TSPAN32 Antibody (Cy5.5)

Binding Specificity: AA 101-200

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TSPAN32

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TSPAN32

Target: TSPAN32 (Tetraspanin 32 (TSPAN32))

Alternative Name: PHEMX/ART1

Background:

Synonyms: ART 1, FLJ17158, FLJ97586, MGC22455, PHEMX/ART1, Pan hematopoietic expression, PHEMX, PHMX, tetraspanin 32, Tetraspanin, tetraspanin32, TSPAN32, TSSC6, Tumor suppressing STF cDNA 6, Tumor suppressing subchromosomal transferable fragment cDNA 6, Tumor suppressing subtransferable candidate 6.

Background: Phemx is a member of the tetraspanin (TM4SF) family of proteins that may be involved in transmembrane signal transduction, regulation of cell proliferation, differentiation and motility. Phemx is a multi-pass membrane protein containing intracellular N- and C-terminal domains, four transmembrane domains and two extracellular loops. It is ubiquitously expressed from early embryogenesis through adulthood. Phemx exhibits predominant expression in hematopoietic tissues suggesting a role in hematopoietic-cell function. In association with the Integrin IIb/Integrin _3 complex, Phemx functions to stabilize arterial thrombi in platelets and regulate outside-in? signaling. This interaction may be important in the process of wound healing. The gene encoding Phemx is located in an important tumor-suppressor gene region that has been associated with Beckwith-Wiedemann syndrome as well as a variety of cancers.

Gene ID: 10077