TSPAN32 antibody (AA 101-200)

Catalog No. ABIN1713566

There is 1 publication for this product available. The Rabbit Polyclonal anti-TSPAN32 antibody is suitable to detect TSPAN32 in samples from Human. It has been validated for IF (cc), IF (p), IHC (p), IHC (fro) and IP.

Quick Overview for TSPAN32 antibody (AA 101-200) (ABIN1713566)

Target: TSPAN32 (Tetraspanin 32 (TSPAN32))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSPAN32 antibody is un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)

Product Details anti-TSPAN32 Antibody

Binding Specificity: AA 101-200

Purpose: ART1 Polyclonal Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TSPAN32

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-TSPAN32 antibody (ABIN1713566)

Tang, Li, Wang, Threadgill, Xiao, Mou, Song, Kuang, Yang, Yang, Gao, Wang, Meng: "ART1 promotes starvation-induced autophagy: a possible protective role in the development of colon carcinoma." in: American journal of cancer research, Vol. 5, Issue 2, pp. 498-513, (2015) (PubMed).

Target Details for TSPAN32

Target: TSPAN32 (Tetraspanin 32 (TSPAN32))

Alternative Name: PHEMX/ART1

Background:

Synonyms: ART 1, FLJ17158, FLJ97586, MGC22455, PHEMX/ART1, Pan hematopoietic expression, PHEMX, PHMX, tetraspanin 32, Tetraspanin, tetraspanin32, TSPAN32, TSSC6, Tumor suppressing STF cDNA 6, Tumor suppressing subchromosomal transferable fragment cDNA 6, Tumor suppressing subtransferable candidate 6.

Background: Phemx is a member of the tetraspanin (TM4SF) family of proteins that may be involved in transmembrane signal transduction, regulation of cell proliferation, differentiation and motility. Phemx is a multi-pass membrane protein containing intracellular N- and C-terminal domains, four transmembrane domains and two extracellular loops. It is ubiquitously expressed from early embryogenesis through adulthood. Phemx exhibits predominant expression in hematopoietic tissues suggesting a role in hematopoietic-cell function. In association with the Integrin IIb/Integrin _3 complex, Phemx functions to stabilize arterial thrombi in platelets and regulate outside-in? signaling. This interaction may be important in the process of wound healing. The gene encoding Phemx is located in an important tumor-suppressor gene region that has been associated with Beckwith-Wiedemann syndrome as well as a variety of cancers.

Gene ID: 10077