TSPAN32 antibody (AA 101-200)

Catalog No. ABIN1713566

Product Details anti-TSPAN32 Antibody

Target: TSPAN32 (Tetraspanin 32 (TSPAN32))

Binding Specificity: AA 101-200

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSPAN32 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TSPAN32

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
IP(1-2 μg)
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-TSPAN32 antibody (ABIN1713566)

Tang, Li, Wang, Threadgill, Xiao, Mou, Song, Kuang, Yang, Yang, Gao, Wang, Meng: "ART1 promotes starvation-induced autophagy: a possible protective role in the development of colon carcinoma." in: American journal of cancer research, Vol. 5, Issue 2, pp. 498-513, (2015) (PubMed).

Target Details for TSPAN32

Target: TSPAN32 (Tetraspanin 32 (TSPAN32))

Alternative Name: PHEMX/ART1 (TSPAN32 Products)

Synonyms: TSPAN32 antibody, ART1 antibody, PHEMX antibody, PHMX antibody, TSSC6 antibody, AW208513 antibody, Art-1 antibody, BB235973 antibody, D7Wsu37e antibody, Phemx antibody, Tssc6 antibody, tetraspanin 32 antibody, TSPAN32 antibody, Tspan32 antibody

Background:

Synonyms: ART 1, FLJ17158, FLJ97586, MGC22455, PHEMX/ART1, Pan hematopoietic expression, PHEMX, PHMX, tetraspanin 32, Tetraspanin, tetraspanin32, TSPAN32, TSSC6, Tumor suppressing STF cDNA 6, Tumor suppressing subchromosomal transferable fragment cDNA 6, Tumor suppressing subtransferable candidate 6.

Background: Phemx is a member of the tetraspanin (TM4SF) family of proteins that may be involved in transmembrane signal transduction, regulation of cell proliferation, differentiation and motility. Phemx is a multi-pass membrane protein containing intracellular N- and C-terminal domains, four transmembrane domains and two extracellular loops. It is ubiquitously expressed from early embryogenesis through adulthood. Phemx exhibits predominant expression in hematopoietic tissues suggesting a role in hematopoietic-cell function. In association with the Integrin IIb/Integrin _3 complex, Phemx functions to stabilize arterial thrombi in platelets and regulate outside-in? signaling. This interaction may be important in the process of wound healing. The gene encoding Phemx is located in an important tumor-suppressor gene region that has been associated with Beckwith-Wiedemann syndrome as well as a variety of cancers.

Gene ID: 10077