ARL1 antibody (AA 101-181) (Cy5.5)

Catalog No. ABIN1706357

The Rabbit Polyclonal anti-ARL1 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect ARL1 in samples from Human.

Quick Overview for ARL1 antibody (AA 101-181) (Cy5.5) (ABIN1706357)

Target: ARL1 (ADP Ribosylation Factor Like GTPase 1 (ARL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARL1 antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-ARL1 Antibody (Cy5.5)

Binding Specificity: AA 101-181

Predicted Reactivity: Human,Mouse,Rat,Sheep,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ARFL1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ARL1

Target: ARL1 (ADP Ribosylation Factor Like GTPase 1 (ARL1))

Alternative Name: ARFL1

Background:

Synonyms: ADP ribosylation factor like 1, ADP-ribosylation factor-like protein 1, ARFL1, Arl1, ARL1_HUMAN.

Background: The ADP-ribosylation factor (ARF) protein family are structurally and functionally conserved members of the Ras superfamily of regulatory GTP-binding proteins (13). ARFs influence vesicle trafficking and signal transduction in eukaryotic cells (13). ARF-dependent regulatory mechanisms include the coordination of spectrin interactions with golgi membranes and the association of actin to the golgi via rho family-dependent G-protein localization (Rac, CDC42) and WASP/Arp2/3 complexes (37). Additionally, ARFs play a central role in maintenance of organelle integrity, assembly of coat proteins, and activation of phospholipase D (57). The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6), members of each class share a common gene organization (8,9). The human ARF6 gene maps to chromosome 7q22.1, contains five exons and four introns, and encodes a 175 amino acid protein (8,9).

Gene ID: 400