ADP Ribosylation Factor Like GTPase 1 (ARL1) (N-Term) antibody

Details for Product No. ABIN965592, Supplier: Log in to see
Antigen
  • ARFL1
  • 2310008D22Rik
  • AU019749
  • zgc:92883
  • 72CDd
  • ARL1
  • ARL1_DROME
  • Arf
  • Arf72A
  • BcDNA:GM20805
  • CG 6025
  • CG6025
  • Dmel\CG6025
  • P25160
  • arf72A
  • arf[72A]
  • arl
  • arl1
  • dARL1p
  • dArl1
  • l(3)72Ae
  • l(3)72CDd
  • arfl1
  • ADP ribosylation factor like GTPase 1
  • ADP-ribosylation factor like GTPase 1
  • ADP-ribosylation factor-like 1
  • ADP-ribosylation factor-like protein 1
  • ADP ribosylation factor-like 1
  • ADP ribosylation factor like GTPase 1 L homeolog
  • ARL1
  • Arl1
  • arl-1
  • arl1
  • arl1.L
Epitope
N-Term
10
10
9
9
8
7
6
6
6
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
84
25
23
4
4
4
4
4
4
3
3
2
1
1
1
Host
Rabbit
83
1
Clonality
Polyclonal
Conjugate
Un-conjugated
7
7
6
5
5
4
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC)
60
43
25
13
7
5
5
4
4
2
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human ARL1(ADP-ribosylation factor-like protein 1)
Purification Purified by antigen-specific affinity chromatography.
Antigen
Alternative Name ARL1 (ARL1 Antibody Abstract)
Background ARL1(ADP-ribosylation factor-like protein 1) belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner. Recent data show that Arl1 regulates the membrane recruitment of Golgin-97, which plays a role in transport from the endosome to the trans-Golgi network.
Application Notes ELISA, Western blotting: 1µg/ml for 2hrs.
Restrictions For Research Use only
Format Liquid
Buffer This antibody is stored in PBS, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Background publications Lu, Tai, Hong: "Autoantigen Golgin-97, an effector of Arl1 GTPase, participates in traffic from the endosome to the trans-golgi network." in: Molecular biology of the cell, Vol. 15, Issue 10, pp. 4426-43, 2004 (PubMed).

Lu, Hong: "Interaction of Arl1-GTP with GRIP domains recruits autoantigens Golgin-97 and Golgin-245/p230 onto the Golgi." in: Molecular biology of the cell, Vol. 14, Issue 9, pp. 3767-81, 2003 (PubMed).

Zhang, Patton, Lee, Liyanage, Han, Rhee, Moss, Vaughan: "Different ARF domains are required for the activation of cholera toxin and phospholipase D." in: The Journal of biological chemistry, Vol. 270, Issue 1, pp. 21-4, 1995 (PubMed).

Product cited in: Van Valkenburgh, Shern, Sharer, Zhu, Kahn: "ADP-ribosylation factors (ARFs) and ARF-like 1 (ARL1) have both specific and shared effectors: characterizing ARL1-binding proteins." in: The Journal of biological chemistry, Vol. 276, Issue 25, pp. 22826-37, 2001 (PubMed).

Hong, Lee, Patton, Lin, Moss, Vaughan: "Phospholipid- and GTP-dependent activation of cholera toxin and phospholipase D by human ADP-ribosylation factor-like protein 1 (HARL1)." in: The Journal of biological chemistry, Vol. 273, Issue 25, pp. 15872-6, 1998 (PubMed).

Did you look for something else?