FTSJ1 antibody (AA 1-110) (Cy5.5)

Catalog No. ABIN1706853

This anti-FTSJ1 antibody is a Rabbit Polyclonal antibody detecting FTSJ1 in IF (cc) and IF (p). Suitable for Mouse and Rat.

Quick Overview for FTSJ1 antibody (AA 1-110) (Cy5.5) (ABIN1706853)

Target: FTSJ1 (FtsJ RNA Methyltransferase Homolog 1 (FTSJ1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FTSJ1 antibody is conjugated to Cy5.5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-FTSJ1 Antibody (Cy5.5)

Binding Specificity: AA 1-110

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FTSJ1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FTSJ1

Target: FTSJ1 (FtsJ RNA Methyltransferase Homolog 1 (FTSJ1))

Alternative Name: FTSJ1

Background:

Synonyms: CDLIV, FTSJ 1, FtsJ homolog 1 E. coli, FtsJ homolog 1, JM23, Mental retardation X linked 44, Mental retardation X linked 9, MRX44, MRX9, Putative ribosomal RNA methyltransferase 1, RRMJ1, SPB1, TRM7, RRMJ1_HUMAN.

Background: FTSJ1 is a 329 amino acid nucleolar protein belonging to the RlmE family and methyltransferase superfamily. Expressed in adult thalamus, hippocampus, amygdala, corpus callosum and caudate nucleus, as well as fetal kidney, lung, liver, brain and lung, FTSJ1 plays a role in rRNA modification and processing. FTSJ1 exists as multiple spliced isoforms which are encoded by a gene located on human chromosome Xp11.23. Notably, defects in the gene encoding FTSJ1 are the cause of mental retardation X-linked type 44 (MRX44) and nonsyndromic X-linked mental retardation (MRX9).