HERC4 antibody (AA 301-400) (Cy7)

Catalog No. ABIN1707556

This Rabbit Polyclonal antibody specifically detects HERC4 in IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for HERC4 antibody (AA 301-400) (Cy7) (ABIN1707556)

Target: HERC4 (Hect Domain and RLD 4 (HERC4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HERC4 antibody is conjugated to Cy7

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-HERC4 Antibody (Cy7)

Binding Specificity: AA 301-400

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HERC4

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HERC4

Target: HERC4 (Hect Domain and RLD 4 (HERC4))

Alternative Name: Herc4

Background:

Synonyms: DKFZP564G092, HECT and RLD domain containing E3 ubiquitin protein ligase 4, HECT domain and RCC1 like domain containing protein 4, HECT domain and RCC1-like domain-containing protein 4, Hect domain and RLD 4, HERC 4, HERC4, HERC4_HUMAN, KIAA1593, Probable E3 ubiquitin protein ligase HERC4, Probable E3 ubiquitin-protein ligase HERC4.

Background: HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).

Gene ID: 26091