GMFG antibody (AA 51-142) (Cy7)

Catalog No. ABIN1707709

This Rabbit Polyclonal antibody specifically detects GMFG in WB, IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for GMFG antibody (AA 51-142) (Cy7) (ABIN1707709)

Target: GMFG (Glia Maturation Factor, gamma (GMFG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GMFG antibody is conjugated to Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-GMFG Antibody (Cy7)

Binding Specificity: AA 51-142

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GMFG/GMF-gamma

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GMFG

Target: GMFG (Glia Maturation Factor, gamma (GMFG))

Alternative Name: GMFG/GMF-gamma

Background:

Synonyms: Glia maturation factor gamma, Glia maturation factor, gamma, GMF GAMMA, GMF-gamma, Gmfg, GMFG_HUMAN, MGC126867.

Background: GMF-gamma is a 142 amino acid protein that belongs to the GMF subfamily of the larger actin-binding protein ADF family. GMF-gamma is expressed predominantly in lung, heart and placenta. GMF-gamma is considered a candidate regulatory growth factor protein, mediating both paracrine and autocrine cell-cell interactions. GMF-gamma is phosphorylated at N-terminal serine, and its phosphorylation is enhanced by coexpression of dominant active Rac 1 and Cdc42. GMF-gamma expression is significantly increased in a cardiac ischemia/reperfusion model where inflammation and angiogenesis take place actively. As a regulator of actin-based cellular functions, GMF-gamma may provide a novel approach to modulate the pathophysiology of cardiovascular diseases. GMF-gamma is primarily found in proliferative and differentiative organs.

Gene ID: 9535