SAPCD2 antibody (AA 301-394) (Cy7)

Catalog No. ABIN1707883

This Rabbit Polyclonal antibody specifically detects SAPCD2 in WB, IF (cc) and IF (p). It exhibits reactivity toward Rat.

Quick Overview for SAPCD2 antibody (AA 301-394) (Cy7) (ABIN1707883)

Target: SAPCD2 (Suppressor APC Domain Containing 2 (SAPCD2))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAPCD2 antibody is conjugated to Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-SAPCD2 Antibody (Cy7)

Binding Specificity: AA 301-394

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C9orf140

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SAPCD2

Target: SAPCD2 (Suppressor APC Domain Containing 2 (SAPCD2))

Alternative Name: C9orf140

Background:

Synonyms: 2010317E24Rik, C9orf140, Chromosome 9 open reading frame 140, SAPC2_HUMAN, p42.3, Protein C9orf140, SAPCD2, Suppressor APC domain containing 2, Suppressor APC domain containing protein 2, TS/MDEP, Tumor specicity and mitosis phase-dependent expression protein.

Background: C9orf140 (chromosome 9 open reading frame 140), also known as TS/MDEP (tumor specificity and mitosis phase-dependent expression protein) or p42.3, is a 394 amino acid nuclear and cytoplasmic protein encoded by a gene that maps to human chromosome 9q34.3. Chromosome 9 consists of about 145 million bases, represents 4 % of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.

Gene ID: 89958