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IDH3B antibody (AA 151-250) (Cy7)

The Rabbit Polyclonal anti-IDH3B antibody has been validated for IF (cc) and IF (p). It is suitable to detect IDH3B in samples from Human.
Catalog No. ABIN1708091

Quick Overview for IDH3B antibody (AA 151-250) (Cy7) (ABIN1708091)

Target

See all IDH3B Antibodies
IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))

Reactivity

  • 53
  • 22
  • 12
  • 6
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 51
  • 2
  • 1
Rabbit

Clonality

  • 53
  • 1
Polyclonal

Conjugate

  • 27
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IDH3B antibody is conjugated to Cy7

Application

  • 27
  • 21
  • 12
  • 12
  • 8
  • 8
  • 3
  • 2
  • 2
  • 1
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Binding Specificity

    • 14
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-250

    Predicted Reactivity

    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human IDH3B

    Isotype

    IgG
  • Application Notes

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))

    Alternative Name

    Idh3b

    Background

    Synonyms: FLJ11043, H-IDHB, IDH3B, IDH3B_HUMAN, Isocitrate dehydrogenase [NAD] subunit beta, Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial, isocitrate dehydrogenase 3, beta subunit, Isocitric dehydrogenase, Isocitric dehydrogenase subunit beta, MGC903, mitochondrial, NAD+-specic ICDH, NAD+-specic ICDH subunit beta, NAD+-specic isocitrate dehydrogenase b subunit, NAD+-specic isocitrate dehydrogenase beta, OTTHUMP00000030023_ OTTHUMP00000030024, RP46.

    Background: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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