PA2G4 antibody (AA 201-320) (Cy7)

Catalog No. ABIN1708194

This anti-PA2G4 antibody is a Rabbit Polyclonal antibody detecting PA2G4 in WB, IF (cc) and IF (p). Suitable for Human, Mouse and Rat.

Quick Overview for PA2G4 antibody (AA 201-320) (Cy7) (ABIN1708194)

Target: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PA2G4 antibody is conjugated to Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-PA2G4 Antibody (Cy7)

Binding Specificity: AA 201-320

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Sheep,Pig,Chicken,Rabbit,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EBP1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PA2G4

Target: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Alternative Name: EBP1

Background:

Synonyms: AA672939, Cell cycle protein p38 2G4 homolog, Cell cycle protein p38-2G4 homolog, ErbB-3 binding protein 1, ErbB3 binding protein 1, ErbB3-binding protein 1, ErbB3-binding protein Ebp1, hG4 1, hG4-1, IRES-specic cellular trans-acting factor 45 kDa, MGC81621, MGC94070, Mpp1, p38 2G4, PA2G4, PA2G4_HUMAN, Plfap, proliferation associated 2G4, proliferation associated 2G4, 38-KD, proliferation-associated 2G4, 38 kDa, proliferation-associated 2G4, a, proliferation-associated protein 1, proliferation-associated protein 2G4, Protein p38-2G4, si:dz150i12.2, wu:fb19b11, wu:ft56d05, zgc:86732.

Background: EBP1 is a member of the peptidase M24C family and functions as an RNA-binding protein involved in cellular proliferation and differentiation processes. It is expressed in a variety of cell lines, including a wide range of tumor cell lines, and localizes to the cytoplasm. Upon treatment with Neuregulin-1 (heregulin), EBP1 translocates to the nucleus. EBP1 is a component of pre-ribosomal ribonucleoprotein complexes, participating in ribosome assembly and regulating the later steps of rRNA processing. In addition, EBP1 interacts with ErbB-3 and may function as a modulator of the ErbB-3-mediated signal transduction pathway by regulating the effects of Neuregulin-1 (heregulin). EBP1 also associates with histone deacetylases (HDACs), functioning as a transcriptional co-repressor of cell cycle regulatory genes.

Gene ID: 5036

Pathways: Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Toll-Like Receptors Cascades