BANF1 antibody (AA 21-89) (FITC)

Catalog No. ABIN1710192

This anti-BANF1 antibody is a Rabbit Polyclonal antibody detecting BANF1 in WB, IF (cc) and IF (p). Suitable for Human.

Quick Overview for BANF1 antibody (AA 21-89) (FITC) (ABIN1710192)

Target: BANF1 (Barrier To Autointegration Factor 1 (BANF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BANF1 antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-BANF1 Antibody (FITC)

Binding Specificity: AA 21-89

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BANF1/BAF

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for BANF1

Target: BANF1 (Barrier To Autointegration Factor 1 (BANF1))

Alternative Name: BANF1/BAF

Background:

Synonyms: BAF, BAF_HUMAN, BANF 1, BANF1, Barrier to autointegration factor 1, Barrier to autointegration factor, Barrier-to-autointegration factor, BCRG 1, BCRG1, BCRP 1, BCRP1, Breakpoint cluster region protein 1, D14S1460, MGC111161.

Background: Barrier-to-autointegration factor (BAF) binds non-specifically to double stranded DNA, possibly to play a role in tissue- or cell type-specific gene expression by interacting with different homeodomain transcription factors. BAF compresses chromatin structure and interacts with the LEM domain of nuclear proteins to play a crucial role in membrane recruitment and chromatin decondensation during nuclear assembly. Additionally, retroviruses like HIV-1 incorporate BAF from host cells into preintegration complexes (PICs) to prevent autointegration of retroviral DNA and thereby promote integration of retroviral DNA into the host chromosome.

Gene ID: 8815